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Program Graduates
The list of program graduates and their doctoral thesis titles is organized by graduation year.
2016
| Graduate Name | Group Leader | Title Of Thesis |
|---|---|---|
| Shradha Das | Knust | Dissecting Crumbs to understand its function in epithelial development of Drosophila embryos |
| Michaela Mickoleit | Huisken | Imaging and reconstructing the beating heart and its morphogenesis |
| Sven Schreiter | Tanaka | Characterization of photoreceptor outer segments phagocytosis in human embryonic stem cell derived retinal pigment epithelium – and its use as a model for compound screening |
| Gopi Shah | Huisken | Pan-embryo Cell Dynamics - Multidimensional imaging uncovers the blueprint of zebrafish development |
| Anne Morbach | Knust | The Role of Cdep in the embryonic morphogenesis of Drosophila melanogaster |
| Andrés Diaz Delgadillo | Hyman | Temperature drives P granule formation in Caenorhabditis elegans |
| Tom Stückemann | Rink | Patterning of the planarian anterior-posterior axis |
| Antje Petzold | Solimena | Degradation of insulin secretory granule cargoes and antigen presentation of peptides thereof in Coxsackievirus B5-infected insulin producing cells |
| Georgios Tsoumpekos | Knust | big bang, a novel regulator of tissue growth in Drosophila melanogaster |
| Kirstin Meyer | Zerial | An in vivo investigation on the mechanosensory function of the mouse liver |
| Stefania Tavano | Huttner | Molecular and cellular mechanisms underlying the role of Insm1 in the generation of basal progenitor cells |
| Sergej Nowoshilow | Tanaka | Transcriptome analysis of axolotl spinal cord and limb regeneration |
| Christopher Schmied | Tomancak | A live imaging paradigm for studying Drosophila development and evolution |
| Anna Erzberger | Salbreux | Actomyosin mechanics at the cell level |
2015
| Graduate Name | Group Leader | Title Of Thesis |
|---|---|---|
| Sarah Mansour | Rink | Tissue polarity specification in planarians |
| Stephanie Spannl-Müller | Eaton | Identification of the protein Ecdysoneless as a regulator of Hedgehog signaling |
| Rahul Glover | Diez | Transport by kinesin motors diffusing on a lipid bilayer |
| Vanessa Carlos | Brand | Notch signaling in the adult zebrafish brain: a comparative study of neurogenic niches |
| Mykola Mylenko | Kurzchalia | Identification and biochemical characterization of food signal in Caenorhabditis elegans |
| Veronika Fitz | Grill | Chromatin transcription by RNA polymerase II - nucleosomal geometry matters |
| Matthias Munder | Alberti | pH - a key regulator of cellular dormancy? |
| Orlando Argüello-Miranda | Zachariae | The regulatory network controlling the transition from prophase I into metaphase I |
| Sandra Richter | Oates | A small molecule screen targeting zebrafish somitogenesis |
| Marta Florio | Huttner | Transcriptional signatures of neocortical expansion - evolutionary role of the human-specific gene ARHGAP11B |
| Mattia Brugiolo | Neugebauer | The dynamic RNA-binding behavior of SR-proteins |
| Sergii Gaidar | Diez | Mechanism of one-dimensional protein diffusion along microtubules |
| Lydia Herzel | Neugebauer | Co-transcriptional splicing in two yeasts |
| Anneke Hibbel | Howard | Characterization of Saccharomyces cerevisiae kinesin Kip2 by total internal reflection fluorescence microscopy |
| Vladimir Despic | Neugebauer | Deciphering the post-transcriptional regulatory network during maternal to zygotic transition in zebrafish |
| Ya-Huei Lin | Knust | The AP2 complex regulates epithelial polarity via regulating Crumbs endocytosis |
| Shang-Yun Liu | Rink | Transcriptomic analysis of molecular wound responses during planarian regeneration |
| Michael Weber | Huisken | All-optical 4D in vivo monitoring and manipulation of zebrafish cardiac conduction |
| Sonja Kroschwald | Alberti | Promiscuous interactions and redundant assembly pathways promote RNP granule formation in Saccharomyces cerevisiae |
| Kerstin Schmidt | Anastassiadis | The role of the H3K4 histone methyltransferase Setd1b during embryogenesis and in adult mice |
| Sebastian Dunst | Eaton | Systematic characterization of Rab GTPase cell type expression and subcellular localization in Drosophila melanogaster |
| Ashish Gupta | Stewart | Role of H3K4 demethylase Kdm5b in the maintenance of mouse embryonic stem cell pluripotency and neural differentiation |
| Oliver Wüseke | Hyman | Pericentriolar material assembly in Caenorhabditits elegans |
| Jan-Philip Medelnik | Tanaka | Cellular and molecular effects of lysophosphatidic acid on cultured human neural progenitor cells |
| Oliver Baker | Anastassiadis | Adapting Nature's toolbox for genome engineering |
| Ivan Radin | Rödel | Functional analysis of the putative mitochondrial copper chaperone AtCox11 |
| Carlos Garzon Coral | Howard | The forces that center the mitotic spindle in the C. elegans embryo |
| Özlem Demir | Howard | Functional characterization of microtubule associated proteins in es cell division and neuronal differentiation |
| Paulina Strzyz | Norden | The significance of bringing nuclei to the apical surface for division in the pseudostratified epithelium of the developing zebrafish retina |
2014
|
Graduate Name |
Group Leader |
Title of Thesis |
|---|---|---|
| Norman Gerstner | Zerial | Endocytic modulation of developmental signaling during zebrafish gastrulation |
| Isabell Weber | Norden | Committed precursor cells in zebrafish retinal development |
| Janine Tittel | Schwille | Actin organization at intracellular membranes: targeting and regulatory interactions of the Spir/formin actin nucleator complex |
| Aida Rodrigo Albors | Tanaka | Cellular and molecular mechanisms underlying spinal cord regeneration in Ambystoma mexicanum |
| Anne Roscher | Jessberger | SWAP-70 regulates osteoclast function by modulating the actin cytoskeleton |
| Mansi Gupta | Brand | Fine-tuning of Fgf8 morphogen gradient by the extracellular matrix |
| Fong Kuan Wong | Huttner | Generation of basal radial glia in the embryonic mouse dorsal telencephalon |
| Melek Kayserili Erkut | Tomanczak | Investigating evolutionary divergence and quantitative traits in population of early Drosophila melanogaster embryos |
| Davi Torres | Stewart | Understanding H3K36 methyltransferases in mouse embryonic stem cells |
| Sebastian Boland | Kurzchalia | Regulation of Caenorhabditis elegans development by an interplay between sterols and glycosphingolipids |
| Liliana Malinovska | Alberti | Specific adaptations in the proteostasis network of the social amoebae Dictyostelium discoideum lead to an unusual resilience to protein aggregation |
| Martin Dressler | Hyman | Dynamics of pericentriolar material during the first cell division of Caenorhabditis elegans embryos |
| Ana Lisica | Grill | Single-molecule study of transcription by RNA polymerase I |
| Ievgeniia Zagoriy | Zachariae | The Role of Polo-like Kinase in Regulating the Prophase-to-Metaphase Transition of Meiosis I |
| Martin Sztacho | Hoflack | F-BAR proteins PSTPIP1 and PSTPIP2 regulate sealing zones in bone resorbing osteoclasts |
| Uddipta Biswas | Jessberger | Dissecting the roles of cohesin complexes in murine spermatocytes |
| Debojyoti Chakraborty | Buchholz | Systematic dissection of long non coding RNAs involved in the regulation of embryonic stem cell pluripotency |
| Annelie Oswald | Oates | Hairy switches and oscillators - reconstructing the Zebrafish segmentation clock |
| Vaishnavi Ananthanarayanan | Tolic-Norrelykke | Dynein dynamics during meiotic nuclear oscillations of fission yeast |
| Martin Machyna | Neugebauer | The central role of RNA-protein interactions in Cajal body structure and function |
2013
| Graduate Name | Group Leader | Title of Thesis |
|---|---|---|
| Marija Podolski | Howard | Characterization of the budding yeast microtubule polymerase Stu2 |
| Peter Hoboth | Solimena | Novel insights into insulin secretory granule dynamics: The relationship between insulin secretory granule age and the cortical cytoskeleton |
| Ana Zarzosa Álvarez | Tanaka | Size control of dorsal root ganglia in developing axolotls |
| Miguel Turrero Garcia | Huttner | Analysis of the cell cycle of neural progenitors in the developing ferret neocortex |
| Oksana Lavrynenko | Shevchenko | Drosophila ecdysteroidome by LC-MS/MS |
| Veikko Geyer | Howard | Characterization of the flagellar beat of the single cell green alga Chlamydomonas reinhardtii |
| Jonathan Rodenfels | Eaton | The role of systemically circulating Hedgehog in Drosophila melanogaster |
| Nikolaos Kyritsis | Brand | The role of inflammation during zebrafish central nervous system regeneration |
| Gamze Gunal | Jessberger | Stage-specific binding profile of cohesin in resting and switch-activated B lymphocytes |
| Annett Duemmler | Tanaka | Characterization of pluripotency genes in axolotl spinal cord regeneration |
| Sophia Millonigg | Eckmann | The translational activator complex GLD-4/GLS-1 regulates germline stem cell self-renewal and differentiation in the adult C. elegans germ line |
| Valentina Botti | Eckmann | Characterization of C. elegans cytoplasmic poly(A) polymerases |
| Patricia Heyn | Neugebauer | Nuclear architecture and gene expression during early zebrafish development |
| Sundar Naganathan | Grill | Regulation of mesoscale physical properties of the C.elegans actomyosin cortex |
| Maryam Aliee | Jülicher | Dynamics and mechanics of compartment boundaries in developing tissues |
| Daniel Lohmann | Thiele | Posttranslational modifications of Ancient ubiquitous protein 1 control intracellular lipid droplet clustering |
| Erdinc Sezgin | Schwille | Continuously variable lipid packing as the principle of functional membrane heterogeneity |
| Nagananda Gurudev | Knust | Identifying genes related to crumbs and elucidating the role of Crumbs in regulating the apical compartment of Drosophila photoreceptor neuron |
| Dennis Kappei | Buchholz | Novel telomere binding proteins |
| Enrico Perini | Zerial | In vitro reconstitution of the molecular mechanisms of vesicle tethering and membrane fusion |
| Ana Stevanovic | Thiele | Structural requirements for targeting of Ancient ubiquitous protein 1 (AUP1) to lipid droplets and discovery of novel regulators of lipid droplet storage |
| Andrew Clark | Paluch | Thickness, dynamics and mechanics of the actomyosin cortex |
| Stephan Saalfeld | Tomanczak | Towards large scale reconstruction of neuro-anatomy at nanometer resolution |
| Rene Schneider | Diez | A novel parabolic prism-type TIR microscope to study gold nanoparticle-loaded kinesin-1 motors with nanometer precision |
| Martin Bergert | Paluch | Mechanics of protrusion formation and bleb-based migration in animal cells |
| Bhavna Rajasekaran | Oates | Analysis of movement of cellular oscillators in the pre-somitic mesoderm of the zebrafish embryo |
| Grzegorz Chwastek | Schwille | Interactions of FCHo2 with lipid membranes |
| Bo-Kai Liao | Oates | Quantitative study of deltaD gene dosage in zebrafish somitogenesis |
| Alexandra Kumichel | Knust | Epithelial cell polarity in the embryonic hindgut of Drosophila melanogaster |
| Andreas Hofmann | Rödel | The mitochondrial phenotype of human mesenchymal stem cells undergoing adipogenic differentiation |
2012
| Graduate Name | Group Leader | Title of Thesis |
|---|---|---|
| Cihan Erkut | Kurzchalia | Molecular mechanisms of anhydrobiosis in Caenorhabditis elegans |
| Iva Kelava | Huttner | Basal radial glia in mammalian neocortical development - insights into brain evolution |
| Davide Accardi | Tolic-Norrelykke | Dynein redistribution during nuclear oscillations in Schizosaccharomyces pombe |
| Andreas Sagner | Eaton | Evolution of planar cell polarity during wing development in Drosophila melanogaster |
| Marcus Jahnel | Grill | Dual-trap optical tweezers for single molecule studies of transcription |
| Madina Karimova | Buchholz | Novel Cre-like site-specific recombinases for genome engineering |
| Senthil Arumugam | Schwille | Reconstitution of bacterial cytokinesis - the Z-ring |
| Shiho Kawamura | Mueller | Characterization of molecular interactions that switch the functional state of native G protein coupled receptors (GPCRS) |
| Cornelia Blei | Jessberger | The role of cohesin SMC1ß and its chromosome association in murine meiosis |
| Simone Fietz | Huttner | Neocortex expansion in the human and ferret - a cell biological and molecular analysis of neural progenitors |
| Marko Storch | Howard | Characterization of microtubule stability regulating kinesins in vitro and introduction of a high throughput technique for studying kinesins on the single molecule level |
| Nicole Bieberstein | Neugebauer | Histone 3 lysine 4 trimethylation and co-transcriptional splicing: a positive feedback loop reinforcing gene expression |
| Andrej Vasilj | Shevchenko | Label-free quantitative mass spectrometry for proteomics |
| Anastasiya Trushko | Howard | Interaction of XMAP215 with a microtubule plus-end studied with optical tweezers |
| Ines Wagner | Tanaka | Identification and proteolytic activation of a serum factor that induces S-phase re-entry in salamander muscle cells |
| Iana Kalinina | Tolic-Norrelykke | Kinetochore capture by intranuclear microtubules in Schizosaccharomyces pombe |
| Maria Begasse | Hyman | Thermal constrains on the embryonic cell division rate and fitness of nematodes |
| Jana Sontheimer | Pisabarro | Functional characterization of proteins involved in cell cycle by structure-based computational methods |
| Roberto Villasenor | Zerial | Regulation of signal transduction by endosomal EGFR distribution |
| Manuel Neetz | Tolic-Norrelykke | Collective behavior of molecular motors |
| Stephanie Protze | Ravens | Transdetermination and lineage reprogramming: promising strategies to generate cardiomyocytes from mature cells? |
| Francisco Pan-Montojo | Funk | Effect of rotenone on the enteric nervous system: implication's in Parkinson's disease pathophysiology |
| Yu Zhu | Tanaka | Reconstitution of three-dimensional neuroepithelia from mouse and human pluripotent stem cells |
| Nikolay Samusik | Zerial | Reconstruction of functional networks from multiparametric high-throughput screens |
| Xicotencatl Gracida Canales | Eckmann | Roles of a nuclear hormone receptor during C. elegans germline development |
| Miguel Coelho | Tolic-Norrelykke | Ageing by passive aggregation and stochastic distribution of protein aggregates |
| Zuzana Markova | Zachariae | Regulation of meiotic prophase by the anaphase-promoting complex |
2011
|
Graduate Name |
Group Leader |
Title of Thesis |
|---|---|---|
| Horatiu Fantana | Howard | Mechanics of spindle centering in Caenorhabditits elegans |
| Lara Planas Paz | Lammert | Mechanoinduction of lymph vessel expansion in the developing mouse embryo |
| Jean Léon Maitre | Heisenberg | Mechanics of adhesion and de-adhesion in zebrafish germ layer progenitors |
| Wilhelm Palm | Eaton | The lipoprotein metabolism of Drosophila melanogaster |
| Rainer Winnenburg | Schröder | Mutations and their role in protein interactions and diseases: computational methods for automated retrieval, analysis and application |
| Alba Diz Muñoz | Paluch | Role of cell protusions during cell migration in vivo |
| Joao Firmino | Knust | A FRAP assay to determine the influence of Crumbs in membrane protein dynamics |
| Franziska Knopf | Weidinger | Bone regenerates via dedifferentiation of osteoblasts in the zebrafish fin |
| Sven Klose | Knust | Investigation of the signal peptide and establishment of a novel structure-function analysis of crumbs in Drosophila melanogaster |
| Paulina Aleksandrowicz | Schnittler | Entry of Ebola virus into host cells |
| Mate Biro | Paluch | Mechanics and regulation of cell cortex assembly |
| Sarah Hochmann | Brand | The role of Fgf signaling in photoreceptor maintenance and degeneration in the adult zebrafish retina |
| Volker Kroehne | Brand | Analysis of brain regeneration in adult zebrafish after traumatic injury |
| Giovanna Ciotta | Stewart | Tagging methods as a tool to investigate histone H3 methylation dynamics in mouse embryonic stem cells |
| Eugeniu Nacu | Tanaka | Understanding cellular and molecular mechanisms of regeneration in Ambystoma mexicanum (axolotl) |
| Claire Poulet | Ravens | Electrophysiological properties of skeletal muscle stem cells: functional evidence of their potential for cardiac differentiation? |
| Giovanni Marsico | Zerial | Analysis of the interplay between endocytosis and cell morphology through the development of computational methods |
| Sider Penkov | Kurzchalia | Trehalose and trehalose lipids in Caenorhabditis elegans dauer larva |
| Aurelie Tomczak | Pisabarro | Discovery of novel chemokines in the human proteome with computational structure-based methods |
| Ana Isabel Fonseca | Hoflack | The role of RhoGEFs, FGD6 and Tiam1, on actin and organelle dynamics in resorbing osteoclasts |
| Radoslaw Ejsmont | Tomancak | A toolkit for visualization of gene expression in live Drosophila embryos |
| Stephan Preibisch | Tomancak | Reconstruction of multi-view microscopic acquisitions |
| Anja Nitzsche | Buchholz | Role of Cohesin in the maintenance of embryonic stem cell identity |
| Fernando Carrillo Oesterreich | Neugebauer | Co-transcriptional splicing in S.cerevisiae |
| Anita Bledau | Anastassiadis | SET histone methyltransferases in mouse embryonic stem cells and mammalian development |
| Veena Kumari | Eaton | Discovery of a novel form of Hedgehog that systematically circulates, and its signaling implications in Drosophila |
| Elena Quesada Hernandez | Heisenberg | The role of cell division orientation during zebrafish early development |
2010
|
Graduate Name |
Group Leader |
Title of Thesis |
|---|---|---|
| Jakub Sedzinski | Paluch | Mechanics of the polar cell cortex during cytokinesis |
| Steffen Jänsch | Hyman | Time-resolved quantification of centrosomes by automated image analysis suggests limiting component to set centrosome size in C. elegans embryos |
| Maria Rostovskaya | Stewart | Lineage commitment of conditionally immortalized bone marrow mesenchymal stromal cells from tetracycline-regulated SV40 large t-antigen transgenic mice |
| Birgit Kagermeier-Schenk | Weidinger | Genome-wide analysis of Wnt/beta-catenin target genes in zebrafish embryogenesis and characterization of a novel modifier of Wnt signaling pathways |
| Maciej Paszkowski-Rogacz | Buchholz | Integration and analysis of phenotypic data from functional screens |
| Gero Fink | Diez | Microtubule organisation by active cross-linking proteins |
| Markus Decker | Hyman | Setting centrosome size in the early Caenorhabditis elegans embryo |
| Mario Schöne | Thiele | Neutral lipid storage in yeast |
| Daniele Soroldoni | Oates | Tracking the oscillations of high-fidelity BAC transgenes during zebrafish somitogenesis |
| Joanna Kalucka | Breier | Relevance of Prolyl HIF hydroxylase 2 (PHD) during embryo development and wound healing |
| Mirjam Mayer | Grill | Mechanics if the C. elegans cell cortex |
| Helena Khaliullina | Eaton | Patched-mediated regulation of smoothened trafficking and activity by Lipophorin-derived lipids |
| Anna Ivanova | Solimena | New method for distinguishing insulin secretory granules by age |
| Andreas Ettinger | Huttner | Release of post-abscission midbodies from stem and cancer cells and potential links to differentiation |
| Kuei-Fang Chung | Bornstein | Isolation and characterization of chromaffin progenitor cells from adult adrenal gland |
| Akhila Chandrashaker | Zerial | Systems analysis of early endosome motility through identification of molecular motors |
| Michael Chopin | Jessberger | Unraveling SWAP-70 functions in B cell ontogeny |
| Michal Surma | Simons | Molecular organization of late secretory pathway in Saccharomyces cerevisiae |
| Shuizi Yu | Brand | Biophysical characterization of fibroblast growth factor 8 signalling and morphogen gradient formation in vivo |
| Corina Oswald | Rödel | Mitochondrial copper homeostasis in mammalian cells |
| Michael Berndt | Diez | Optical Near-fields in fluorescence microscopy - techniques to access information in the third dimension on the nanometer scale |
| Elwy Okaz | Zachariae | The role of proteolysis in regulating entry into the first division of meiosis |
| Christian Schroeter | Oates | Segmentation clock dynamics in zebrafish her gene mutants |
| Julio Sampaio | Simons | The role of lipids in cellular architecture and function |
| Hermann-Josef Kaiser | Simons | Membrane order and domain formation in cholesterol-containing membranes |
| Heiko Keller | Schwille | New in vitro model for studying the influence of HIV-1 gag assembly on lateral membrane organization |
| Dorian Freudenreich | Brand | Genetic cell lineage tracing and transcriptome analysis of neuronal progenitor cells during neurogenesis and regeneration of the adult zebrafish telencephalon |
| Martin Loose | Schwille | Self-organization of min proteins in vitro |
| Jan Eglinger | Lammert | A mechanism of cascular lumen widening revealed by an angiogenesis screen |
| Judith Schenk | Huttner | Interkinetic nuclear migration and centrosome positioning in mammalian neural progenitors: the role of non-muscle myosin II |
| Daniela Roelig | Oates | The role of the Hes5 gene family in the evolution of the somitogenesis clock |
| Adriana Klyszejko | Mueller | Investigating structure and assembly of the energy conversion machinery of the cell by atomic force microscopy |
| Agata Rybarska | Eckmann | he novel protein GLS-1 modulates conserved mRNA regulatory machinery and has important roles in C. elegans germline development |
| Katharina Landsberg | Dahmann | The role of cell bond tension in directing cell sorting at the anteroposterior compartment boundary in wing imaginal dices of Drosophila melanogaster |
| Christine Moessinger | Thiele | Identification, regulation and physiological role of enzymes involved in triacylglycerol and phosphatidylcholine synthesis on lipid droplets |
| Karolina Jastrezbowska | Tomancak | Evolution of gene expression regulation during embryonic development of Drosophila species |
| Livia Goto Silva | Zerial | Characterization of APPL signalling endosomes in neurons |
| Nadine Muschalik | Knust | Epithelial cell polarity and photoreceptor morphogenesis in Drosophila |
| Garrett Greenan | Hyman | Setting mitotic apindle length in the early Caenorhabditis elegans embryo |
2009
| Graduate Name | Group Leader | Title of Thesis |
|---|---|---|
| Thomas Widmann | Dahmann | The role of Dpp and Wingless signaling gradients in directing cell shape during Drosophila wing imaginal disc development |
| Estelle Festor | Jessberger | Role of SMC1beta in meiosis |
| Jesse Lipp | Zachariae | Control of reductional chromosome segregation in meiosis |
| Till Korten | Diez | How Kinesin-1 deals with roadblocks:biophysical description and nanotechnological application |
| Vyacheslav Zagoriy | Kurzchalia | Long chain O-ascarosyl alkendiols (ascarosides) of Caenorhabditis elegans |
| Magno Junqueira | Shevchenko | Systematic characterization of mammalian protein complexes by shotgun liquid chromatography tandem mass spectrometry |
| Annalisa Marsico | Schröder | Discovery and characterization of new structural and functional motifs in alpha-helical transmembrane proteins with an application to interpret Single Molecule Force Spectroscopy data |
| Anna Sedello | Buchholz | Loss-of-functionscreen for proteins cooperating with Runx1 in hematopoiesis and leukemogenesis |
| Marta Pabis | Neugebauer | The cap-binding complex promotes co-transcriptional splicing in vivo |
| Dragomir Krastev | Buchholz | An RNA interference synthetic interaction screen identifies vulnerability factors for TP53 mutant cells |
| Manonmani Arunachalam | Tomancak | Computational discovery of cis-regulatory elements in multiple Drosophila species |
| Britta Jedamzik | Eckmann | mRNA targets of GLD-3 in Caenorhabditis elegans |
| Jens-Christian Roeper | Eaton | The influence of cell mechanics, cell-cell interactions and proliferation on epithelial packing |
| Johanna Spandl | Thiele | Cell biology of lipid droplets: the function of the lipid droplet protein AUP1 and establishment of the novel fluorescent dye LD540 for improved staining and imaging of lipid droplets |
| Tatsiana Audzevich | Jessberger | The function of SWP-70 in CD40/IL-4 induced beta cell activation and immunoglobulin E class switch recombination |
| Waldemar Kanczkowski | Bornstein | The role of toll-like receptors in the human adrenal gland |
| Petra Stockinger | Heisenberg | Regulation of tangentialbranchiomotor neuron migration in zebrafish |
| Jeremy Pulvers | Huttner | The roles of the genes Aspm and Brca1 in the development of the mouse neocortex |
| Christian Klose | Simons | Membrane organization in yeast |
| Slava Stamova | Rieber | Polyclonal tumor-specific activation of cytotoxic effector cells by bispecific antibody constructs |
| Maria Joao Carvalho | Eaton | Steraol requirements in Drosophila melanogaster |
| Julia Massier | Thiele | siRNA screen for the identification of novel genes regulating lipid droplet metabolism in a human cell line |
| Falko Riedel | Eaton | Core members of the Drosophila melanogaster LDL receptor family and their function in wing development |
| Marzuk Kamal | Howard | Coupling between membrane-curvature and lipid geometry |
| Claudio Collinet | Zerial | Systems survey of endocytosis by functional genomics and quantitative multi-parametric image analysis |
| Volker Bormuth | Howard | Optimized optical tweezers to study the mechanics of Kinesin-8: stepping, slipping, protein friction |
| Charles Bradshaw | Zerial | Improving the analysis of genome-wide screens trough the detection of weakly conserved domains |
| Daniel Lingwood | Simons | The activation of organization in cell membranes |
| Sven Vogel | Tolic-Norrelykke | The mechanism of meiotic nuclear oscillations in Schizosaccharomyces pombe |
| Thomas Hannich | Kurzchalia | Lipid methylation in the development of Caenorhabditis elegans |
| Cordula Reuther | Diez | Patterning planar surfaces with motor proteins: towards spatial control over motile microtubules |
| Diana Kadner | Brand | Mechanism of cell adhesion at the midbrain-hindbrain neural plate in the teleost danio rerio |
| Julia Ganz | Brand | Subdivisions and molecular characteristics if the neurogenic niches in the adult zebrafish telecephalon |
| Anne Meyer | Reichmann | Intracellular signaling pathways in the dopaminergic specification of fetal mesencephalic neural stem cells |
| Nathalie Wielsch | Shevchenko | Optimized GeLC-MS/MS for botom-up proteomics |
| Maria Kolanczyk | Brand | Signaling mechanisms and developmental function of fibroblast growth factor receptors in zebrafish |
| Boris Strilic | Lammert | Molecular mechanism of vascular lumen formation in the dorsal aorta of mice |
| Stefanie Redemann | Hyman | The role of the acto-myosin cortex for forcegeneration and spindle positioning in the C.elegans embryo |
| Fuat Aksoy | Pompe | Interaction of metal nanoparticles with fluorophores and their effect of fluorescence |
| Mark Schmid | Eckmann | GLD-4, a poly(A) polymerase affecting germ development in C. elegans |
| Fernando Ugarte Verdugo | Roesen-Wolff | Role of Notch signalling pathway in human mesenchymal stem cell differentiation |
| Roberto Iacone | Anastassiadis | Lineage commitment screens in mES cells using a tetracycline inducible cDNS library |
| Vladimir Mazurov | Tanaka | Lineage commitment screens in mES cells using a tetracycline inducible cDNS library |
2008
|
Graduate Name |
Group Leader |
Title of Thesis |
|---|---|---|
| Bert Nitzsche | Diez | Optical 3D-nanometry to study the function of biomolecular motors in nanotransport |
| Natalya Baltrukovich | Mueller | Mechanical unfolding of membrane proteins captured with single-molecule AFM techniques |
| Magalie Lebreton | Kurzchalia | New outlooks on the transport of cholesterol in Caenorhabditis elegans |
| Leah Herrgen | Oates | The regulation of segmentation clock period in zebrafish |
| Jifeng Fei | Huttner | Studies on the progeny of neuronal progenitors in the developing mouse brain using novel transgenic models of the tis21 locus |
| Ana Fonseca | Corbeil | New insights into cell migration and asymmetric cell division of human hematopoietic progenitors |
| Konstantin Doubrovinski | Kruse | Physical approaches to cytoskeletal self-organization |
| Adam Kupinski | Eckmann | The Ste20 kinease GCK-3 is essential for C. elegans development and regulates centrosome maturation during meiosis |
| Mathias Gerl | Simons | Membrane domains and traffic in epithelial cells |
| Mikolaj Slabicki | Buchholz | A systematic investigation of DNA double strand break repair by a genome-wide RNAi screen in human cells |
| Sabine Buschhorn | Simons | Functional implication of lipid organization in MDCK cells |
| Axel Erler | Stewart | Family ties: characterization of DNA annealing protein reveal a new model or the initiation of homologous recombination |
| Philipp Weissert | Tanaka | Bmp proteins in urodele myotube cell cycle re- entry and in regeneration |
| Christin Suess | Solimena | mRNA binding proteins as early response factors of stimulated insulinoma INS-1 cells |
| Julia Winter | Zerial | Genome-wide analysis of membrane trafficking in polarised epithelial cells in the C.elegans intestine |
| Magdalena Strzelecka | Neugebauer | The essential role of cajal bodies in embryonic development |
| Luke Buchanan | Stewart | Mechanisms of chromatin state definition in Schizosaccharomyces pombe |
| Maria Aranzazu Sanchez Fernandez | Pompe | Role of osteoclasts in bone formation and bone microenvironment |
| Zuzana Kirsnerova | Baretton | The role of Hypoxia inducible factors in physiological and pathological angiogenesis |
| Marta Luz | Brand | Cellular mechanisms involved in Wnt8 distribution and function in zebrafish neurectoderm patterning |
| Fernando Fierro Becker | Ehninger | Definition of molecular pathways with importance for the interaction of leukemic blasts with mesenchymal stem cells |
| Vladimir Varga | Howard | Characterization of Saccharomyces cerevisiae kinesin-8 by single-molecule fluorescene microscopy |
| Tobias Heckel | Hoflack | Revealing Src tyrosine kinase-dependent signaling pathways in osteoclasts: Implications on actin organization and cell polarity |
2007
|
Graduate Name |
Group Leader |
Title of Thesis |
|---|---|---|
| Sina Koch | Ehninger | Aberrant subcellular localization as a potential mechanism contributing to the abnormal signaling of the mutant Flt3-ITd receptor tyrosine kinase in acute myeloid leukemia |
| Susanne Mende | Reichmann | Alterations in nuclear gene expression profiles in response to mitochondrial dysfunction |
| Marcello Maresca | Stewart | Fundamental and applied studies on phage mediated recombination |
| Jakob Suckale | Solimena | Polypyrimidine tract-binding protein in knockdown mouse models |
| Lara Carvalho | Heisenberg | The role of yolk syncytial layer in blastoderm movements during gastrulation in zebrafish |
| Nicola Bauer | Corbeil | New insights into the plasma membrane dynamics of rare stem cells by studying the prominin molecule |
| Yvonne Gloor | Walch-Solimena | The Arf GTPase exchange factor sec7p interaction network: unraveling the crosstalk between key regulators of golgi transport |
| Joao Matos | Zachariae | Regulation of chromosome segregation in meiosis |
| Cagri Sakalar | Stewart | The role of H2A.z in fission yeast chromatin |
| Amani Said | Dahmann | Mechanisms underlying cell sorting at the A-P compartment boundary in the Drosophila wing |
| Ruiyu Zhu | Rieber | Molecular analysis of a RNA surveillance escape mechanism leading to systemic autoimmunity |
| Martin Kragl | Tanaka | Studying the patterning mechanisms and cell fates during limb regeneration in Ambystoma mexicanum |
| Thomas Ohrt | Schwille | Elucidating the intracellular mechanisms of RNA interference by single molecule fluorescence microscopy and spectroscopy |
| Vinciane Grimard | Thiele | MAPK9: A new regulator of triglyceride metabolism revealed by siRNA screening |
| Eva-Maria Schoetz | Heisenberg | Dynamics and mechanics of zebrafish embryonic tissues |
| Jennifer Fish | Huttner | The evolution of neuronal progenitor cell division in mammals: the role of the abnormal spindle-like microcephaly associated (Aspm) protein and epithelial cell polarity |
| David Cisneros Armas | Mueller | Molecular assemblies observed by atomic force miscroscopy |
| Serap Günes | Modification of vesicular stomatitis virus G protein for targeted gene delivery into PSCA-positive tumor cells | |
| Anne-Lore Schlaitz | Hyman | Setting mitotic spindle length in the early Caenorhabditis elegans embryo |
| Robin Klemm | Simons | Lipid rafts in protein sorting and yeast cell polarity |
| Raluca Constantinescu | Reichmann | Oxidative stress involvement in new cell culture models of Parkinson´s disease |
| Ana Cunha | Rieber | Evaluation of D-TMPP for use in diagnosis and specific cellular immunotherapy of prostate cancer |
| Nicola Watt | Reichmann | Mitochondrial dysfunction and lipid metabolism in cell culture models of respiratory chain and neurodegenerative diseases |
| Tim Noetzel | Hyman | Control of microtubule dynamics by XMAP215 and XTACC3 |
| Tanuj Sapra | Mueller | Single-molecule measurements of complex molecular interactions in membrane proteins using atomic force microscopy |
| Laura Buffa | Solimena | Cell biology of the ICA69 protein family in neurosecretory cells |
| Christer Ejsing | Simons | Molecular characterization of the lipidome by mass spectrometry |
| Anna Grzyb | Huttner | Characterization of Y-box protein 3 (MSY3) in the developing murine central nervous system |
| Susanne Bechstedt | Howard | Mechanotransduction in Drosophila melanogaster |
| Henrik Bringmann | Howard | Experiments concerning the mechanism of cytokinesis in Caenorhabditis elegans embryos |
2006
|
Graduate Name |
Group Leader |
Title of Thesis |
|---|---|---|
| Alessio Attardo | Huttner | Novel in vivo imaging approaches to study embryonic and adult neurogenesis in the mouse |
| Mihail Sarov | Stewart | A recombineering pipeline for functional genomics applied to Caenorhabditis elegans |
| Heather Mortiboys | Reichmann | Influence of mitochondrial energy metabilism on cellular function: implication for neurometabolic and neurodegenerative diseases |
| Coralie Apfeldorfer | Hoflack | Lyosome biogenesis during osteoclastogenesis |
| Alexej Kedrov | Mueller | Observing molecular interactions that determine stability, folding, and functional states of single Na+/H+ antiporters |
| Gaspare Benenati | Kurzchalia | Osmotic balance and establishment of polarity in the C.elegans embryo require cytochrome P450 CYP31A |
| Alvaro Crevenna | Howard | Kinesin-1 mechanical flexibility and motor cooperation |
| Sabine Witzel | Heisenberg | Local WNT11 signalling and its role in coordinating cell behaviour in zebrafish embryos |
| Christina Eugster | Eaton | The glypican Dally binds to Lipophorin particles and increases Hedgehog signaling efficiency |
| Ralf Kittler | Buchholz | Functional genomic analysis of cell cycle progression in human tissue culture cells |
| Irena Konstantinova | Lammert | EphA-ephrin-A bidirectional signaling amplifies insulin secretion from beta-cells |
| Maike Gravert | Walch-Solimena | Novel regulators of trafficking in the yeast Golgi-endosomal system |
| Indrani Sarkar | Buchholz | Directed evolution of an HIV-1 LTR specific recombinase for anti-retroviral therapy - a proof of concept study |
| Lucie Kalvodova | Simons | Reconstituting APP and BACE in proteoliposomes to characterize lipid requirements for beta-secretase activity |
| Thorsten Baust | Hoflack | Proteomic analysis of the sorting machineries involved in vesicular traffic between the biosynthetic |
| Ganka Nikolova | Lammert | The vascular basement membrane: a niche for insulin gene expression and beta cell proliferation |
| Anne-Kathrin Classen | Eaton | Hexagonal packing of Drosophila wing epithelial cells by the planar cell polarity pathway |
| Imke Listerman | Neugebauer | On co-transcriptional splicing and U6 snRNA biogenesis |
| Serena Bielli | Dahmann | Characterization of the EGFL7/8 ortholog during Drosophila oogenesis |
| Fabio Demontis | Dahmann | Modeling human Usher syndrome during Drosophila melanogaster development |
| Werner Straube | Tanaka | Purification of a serum factor that triggers cell cycle re-entry in differential newt myotubes |
| Cerasela Dinu | Howard | Leveraging the motor protein Kinesin to manipulate DNA molecules in synthetic environment |
| Lidia Sobkow | Tanaka | Development of transgenic Ambystoma mexicanum (axolotl) to study fate during development and regeneration |
| Sandra Schubert | Solimena | The role of Beta2-syntrophin phosphorylation in secretory granule exocytosis |
| Vinzenz Link | Heisenberg | Identification of proteins controlling gastrulation movements by a proteomic approach in zebrafish |
| Tobias Oelschlaegel | Zachariae | Meiosis-specific regulations of the anaphase-promoting complex |
| Ihor Zahanich | Ravens | Differentiation potential of human mesenchymal stem cells: expression of molecular markers, ion channels and gap junction channels |
| Oleh Khalimonchuk | Rödel | Yeast mitochondrail copper metabolism: topology ND ROLE OF COX11P |
| Naomi Foster | Gonzalez | The involvement of ARF6 in rapid membrane recycling during Drosophila spermatocyte cytokinesis |
2005
|
Graduate Name |
Group Leader |
Title of Thesis |
| Andriy Kovalchuk | Barth | Molecular analysis of the LTR retrotransposon Ylt1 from the genome of dimorphic fungus Yarrowia lipolytica |
| Sandra Lubitz | Stewart | Analysis of an epigenetic regulator in mouse embryonic stem cell - self-renewal and differentiation |
| Stephanie Schonegg | Hyman | Rho GTPase family members in establishment of polarity in C. elegans embryos |
| Sebastian Höpfner | Zerial | Modulation of cargo transport and sorting through endosome motility and positioning |
| Bartosz Balana | Ravens | Influence of culture conditions on differentiation and bioelectrical properties of human mesenchymal stem cells |
| Nurhan Ozlu | Hyman | The mitotic spindle assembly in C. elegans embryos |
| Lars Demmel | Walch-Solimena | Unraveling phosphatidylinositol 4-kinase function in the yeast Golgi-endosomal system |
| Monika Suchanek | Thiele | Regulation of lipid homeostasis - mechanisms of sterol sensing |
| Florian Ulrich | Heisenberg | Regulation of zebrafish gastrulation movements by slb/wnt 11 |
| Lars Kürschner | Thiele | Polyene lipids: a novel tool to study lipids |
| Tomasz Proszynski | Simons | Protein sorting and cell surface polarity in yeast |
| Mirko Trajkovski | Solimena | Regulated secretion and gene expression in beta-cells: link through ICA512 |
| Zuzana Kronekova | Rödel | Assembly of mitochondrial ubiquinol-cytochrome c oxireductase complex in yeast Saccharomyces cerevisiae: the role of Cbp3p and Cbp4p assembly factors |